26 October 2012

Are you afraid of Alzheimer's disease? Do not be late with the start of HRT!

In post-menopause, a five-year time window has been found to reduce the risk of dementia

Medical news based on the materials of Medical Daily:
Starting Hormone Therapy Within 5 Years After Menopause Cuts Alzheimer's Disease Risk by Nearly a ThirdStarting hormone replacement therapy strictly within five years after menopause reduces the risk of developing Alzheimer's disease by a third, while a later start of such therapy does not affect the likelihood of dementia in any way.

However, those women who start taking female hormones at the age of about 65 have an increased risk of developing Alzheimer's disease.

These are the results of a study designed to clarify conflicting information about the relationship between Alzheimer's disease and hormone replacement therapy, conducted by a group of specialists from leading American research centers. The fact is that, on the one hand, there was scientific data on the positive effect of taking female hormones after menopause on the brain function of women, and on the other hand, the results of clinical studies did not confirm this information.

The authors analyzed information on 1,768 women aged 65 years and older who, from 1995 to 2006, participated in a large-scale study of the influence of genetic and environmental factors on the development of dementia in elderly residents of Cache County, Utah (Cache County Study), during which they, among other things, provided detailed information about the age of menopause and the mode of use of hormone replacement therapy.

1,100 participants reported taking or taking hormones – either estrogen alone or in combination with progestin, while 668 did not. During the study period, 176 women developed Alzheimer's disease, including 87 from the hormone-taking group and 89 from the control group.

The analysis showed that after the onset of menopause, there is a five-year window critical for preventing the onset of dementia, when taking female hormones reduces the risk of developing the disease by 30 percent, especially if therapy then continues for ten or more years. In the case when hormone intake begins after the "closing" of this five-year window, there is no connection between therapy and the onset of Alzheimer's disease. This, however, does not apply to the case when a woman whose age is approaching 65 begins to take hormones – then the risk of developing dementia increases.

Despite the unambiguity of the results obtained, the authors whose work was published on October 24 in the journal Neurology (Shao et al., Hormone therapy and Alzheimer's disease dementia. New findings from the Cache County Study), suggest that it is too early to include them in medical recommendations for older women, as additional research is required.

Portal "Eternal youth" http://vechnayamolodost.ru26.10.2012

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