By urine analysis
A non-invasive test detects bladder cancer better than others
Svetlana Maslova, Hi-tech+
The new test is simple and effective: the patient just needs to pass urine, and it will determine the presence of a tumor. The technique will make it unnecessary to insert a tube with a video camera into the urethra and a biopsy.
Researchers from Tufts University (USA) has developed a non-invasive method for detecting bladder cancer, which will make the examination simpler, faster and more accurate compared to modern diagnostic methods. The new urine test is even more effective than a visual examination, according to a press release from Researchers develop accurate, a non-invasive method to detect bladder cancer.
Article Sokolov et al. Noninvasive diagnostic imaging using machine-learning analysis of nano-resolution images of cell surfaces: detection of bladder cancer is published in the journal PNAS – VM.
Modern screening includes cystoscopy – the insertion of a tube with a video camera into the urethra, as well as a biopsy of a tissue sample. Against the background of frequent cases of cancer recurrence – up to 50-80% – the examination should be carried out every 3-6 months, which makes diagnosis expensive and uncomfortable.
The new urine test is simpler and more accurate. It is enough to submit a sample of biomaterial, and the doctor will soon have an informative picture of the patient's health, the authors emphasize.
The analysis detects cancer in more than 90% of cases, while other modern methods demonstrate sensitivity from 20% to 80%.
The test is based on the discovery of scientists who discovered that bladder cells in a cancer patient have unique surface features that distinguish them from healthy ones. These cells are released from the body in the urine, which makes it possible to make an immediate diagnosis using atomic force microscopy.
Other teams have recently presented positive results in the diagnosis of oncological diseases. In the USA, it has been proven that PET scans can detect tumors even before lung cancer begins, and Canadian scientists have developed a blood test to diagnose all types of cancer at once.
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