05 June 2019

From hypertension and dementia

Blood pressure medications reduce the risk of age-related dementia

Sergey Kolenov, Hi-tech+

According to a study by German scientists conducted on 24,000 patients, popular anti-hypertension drugs can delay the onset of dementia or even avoid it. But in order for the effect to be more significant, treatment should be started as early as possible.

Researchers from Germany, whose work tells Science Daily, decided to find out how different drugs affect the risk of developing dementia. To do this, they analyzed information from the medical database Disease Analyzer (IQVIA), where general practitioners anonymously enter data on patients, diagnoses and prescribed medications. The study included more than 24,000 patients with hypertension older than 60 years. All of them had hypertension, and half also had dementia.

As a result, it turned out that patients who took medications against high blood pressure were less likely to develop dementia. First of all, we are talking about angiotensin II receptor blockers, angiotensin-converting enzyme inhibitors and beta blockers.

The researchers emphasize that taking medications against hypertension alone does not guarantee complete protection against dementia.

However, these drugs can slow down the cognitive decline associated with high blood pressure. They emphasize that hypertension treatment should be started as early as possible.

In the future, the team plans to investigate what effect antidepressants, drugs that reduce blood lipid levels, as well as other medications have on the risk of developing dementia.

Article by Bohlken et al. The Relationship Between the Use of Antihypertensive Drugs and the Incident of Dementia in General Practices in Germany is published in the Journal of Alzheimer's Disease – VM.

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