Retinal cells for the treatment of blindness have been grown in the laboratory on a nanoframe
Researchers have found a way to create three-dimensional "scaffolds" to grow retinal cells in the lab.Researchers at Anglia Ruskin University have used nanotechnology to grow retinal pigment epithelial cells. The cells grown on the tiny framework remain healthy and viable for up to 150 days. The research opens up a new way to treat a common cause of developing blindness in the future.
Scientists used "electrospinning" technology to create a framework on which PES cells could grow. This is a way of producing polymer nanofibers by applying electrostatic forces to an electrically charged stream of polymer solution or melt. The researchers coated the printed scaffolds with the steroid fluocinolone acetonide, which protects against inflammation, increases cell resistance and promotes eye cell growth.
Previously, scientists had grown retinal pigment epithelial cells on a flat surface, which had no practical value for therapy. The analysis showed that in the three-dimensional environment of the steroid-coated nanocage, the cells develop more efficiently and create structures that can later be used for transplantation.
Age-related macular degeneration is the most common cause of vision loss in older adults. As the population ages, this problem will spread. One possible cause is changes in Bruch's membrane, which supports the retinal pigment epithelium cells, and destruction of the x