Drug addicts were allowed to "file"

The first implant for the treatment of opioid addiction has been approved in the USA

Oleg Lischuk, N+1

Probuphine implant. Photo by Braeburn Pharmaceuticals

The U.S. Food and Drug Administration (FDA) has approved the first implant for the replacement therapy of opioid dependence, according to a press release from the organization (FDA approves the first buprenorphine implant for treatment of opioid dependence).

A subcutaneous implant called Probuphine consists of four rod-shaped ProNeura drug delivery systems 2.5 centimeters long, which are placed under the patient's skin in the shoulder area. They contain a partial (partial) agonist of opioid receptors buprenorphine and ethylene vinyl acetate, which ensures its uniform gradual release within six months. The system was developed by Titan Pharmaceuticals and Braeburn Pharmaceuticals.

The basis for the FDA's decision was the results of placebo-controlled clinical trials involving 163 and 287 people. 63 percent of them refrained from administering illegal opioids for 24 weeks. The therapeutic system is approved for use in those patients who are stabilized on low or moderate doses of buprenorphine in the form of tablets or buccal (cheek) films.

"Opioid abuse and addiction bring great hardship to American families. We must do everything to introduce new methods of treatment that will help patients regain control of their lives. Today's decision will give patients the first implant supporting their efforts to continue therapy as part of a general rehabilitation program," said FDA spokesman Robert Califf.

It is estimated that about 2.1 million US residents are addicted to prescription opioids and another 467 thousand are addicted to heroin. The number of overdose deaths has quadrupled since 1999 to 28,647 in 2014.

Substitution therapy for opioid addiction is the replacement of illegal drugs with pharmacy drugs containing a known amount of purified active substance and taken orally. This significantly reduces the risk of overdose and complications associated with non-sterile injections. Full opioid receptor agonist methadone or partial – buprenorphine are usually used as drugs for substitution therapy. In some countries, an industrially produced sterile heroin solution is also approved for the treatment of severe addiction. Substitution therapy is used in many countries of the world, it is prohibited in Russia.

Portal "Eternal youth" http://vechnayamolodost.ru  27.05.2016