He's not bad!
Scientists claim that "bad cholesterol" is just an overblown myth
Valeria Sema, "Mednovosti"
A new review of research over the past fifty years, made by an international group of doctors and published in the Expert Review of Clinical Pharmacology, challenges the half-century-old belief that "bad cholesterol" (low-density lipoproteins, LDL) causes cardiovascular diseases.
Cardiologists from the USA, Sweden, Great Britain, Italy, Ireland, France, Japan and other countries (17 people in total) We found no evidence of a link between high levels of total or "bad" cholesterol and cardiovascular diseases, analyzing data from 1.3 million patients. They stated: this view is based on "misleading statistics, excluding failed trials, and ignoring numerous contradictory observations."
The review also raises the question of the use of statins as the main means of preventing cardiovascular diseases. This may have a serious resonance, since tens of millions of people are currently taking statins to lower cholesterol and prevent myocardial infarction.
"For decades, studies have been conducted designed to mislead the public and doctors, it was assured that LDL causes heart disease, but in fact it is not," said one of the authors of the review, David Diamond, PhD, professor of Psychology and Molecular Pharmacology and Physiology at the University of South Florida (University of South Florida). – The study that targeted LDL is terribly wrong. Not only is there no evidence of a causal relationship between LDL and heart disease, but the statistical approach that statin advocates used to demonstrate benefits was deceptive."
The effectiveness of statin treatment as a primary prevention has been discussed by researchers for several decades. The review states that these drugs have "non-obvious benefits, and serious side effects." An analysis of data in 12 European countries from 2000 to 2012 showed that there was no link between statin intake and a reduction in mortality.
Currently, the review notes, statements about positive results of statin tests have "evaporated", since, according to the rules introduced in 2005 by the health authorities of Europe and the United States, all sample data must be made public.
"We suggest that clinicians abandon the use of statins and PCSK9 inhibitors, and instead identify and identify the actual causes of cardiovascular diseases," said the co-author of the review, Sherif Sultan from the Galway Clinic in Ireland, professor of the International Society for Vascular Surgery.
The researchers found a curious thing: in patients with acute myocardial infarction, the level of "bad" cholesterol was below normal, and in healthy people with low "bad" cholesterol, the risk of infectious diseases and cancer was significantly increased. But the most important finding was that elderly people with high LDL levels live the longest.
Thus, a high level of "bad" cholesterol is beneficial in terms of overall life expectancy. And in order to prevent cardiovascular diseases, it is recommended to follow a low-carb diet for weight loss.
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