Genes, cells and biotechnologies

Information reference: Sergey Kiselyov

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On November 30 (Sunday), Sergey Kiselyov, Chief Researcher of the Vavilov Institute of General Genetics of the Russian Academy of Sciences, will speak as part of the Festival of Public Lectures #KNOW. The topic of the lecture is "Genes, cells and biotechnologies".

Sergey Lvovich Kiselyov – Professor, Doctor of Biological Sciences, Scientific Director of the Epigenetics Department, Chief Researcher at the Vavilov Institute of General Genetics of the Russian Academy of Sciences.

Graduated from the Moscow Engineering Physics Institute in 1982, worked at the All-Russian Research Institute of Genetics for Cloning Plant Genes (Vinetsky Yu.P. laboratory), since 1988 worked at the Institute of General Genetics of the Russian Academy of Sciences, then moved to the Institute of Gene Biology of the Russian Academy of Sciences, where since 1995 he worked in the laboratory of G.P. Georgiev. Since 1999 – Head of the Cancer gene Therapy group, since 2001 – Head of the Laboratory of Molecular Genetics of Cancer.

Author of more than 80 works (30 of them in foreign publications). One of the creators of the first Russian and third in the world gene therapy drug for the treatment of ischemic conditions. He developed in vitro models of diseases to study the mechanisms of pathology and search for medicines.

Laureate of the prize of the Government of the Russian Federation for the development of new methods of cancer biotherapy. The area of scientific interests of the scientist: early embryonic development, reprogramming, epigenetics of reprogramming, creation of models of socially significant and rare diseases, methods of treatment and screening of drugs, gene and cell therapy.

3 facts about Sergey Kiselyov:One of the creators of the first Russian and third in the world gene therapy drug for the treatment of ischemic conditions.

2. As a researcher at the Vavilov Institute of General Genetics of the Russian Academy of Sciences, he is actively researching ways to treat cancer. In 2000, together with the staff of the N.N. Blokhin Russian Research Center of the Russian Academy of Medical Sciences in Moscow and the N.N. Petrov Research Institute of Oncology in St. Petersburg, he developed a number of gene-therapeutic approaches to block the blood supply to the tumor. The result was stabilization of diseases in 25% of cases and partial regression of the tumor in 7% of cases.
3. Laureate of the prize of the Government of the Russian Federation for the development of new methods of cancer biotherapy.

3 facts about biology:The journal Science named cancer immunotherapy as the main achievement in biology and medicine in 2013.

1. Another achievement was called the CRISPR genome editing technology (Clustered Regularly Interspaced Short Palindromic Repeats, translated from English as short palindromic repeats, regularly arranged in groups). With the help of the Cas9 protein, scientists have learned to edit genetic information very accurately. This will allow in the research and treatment of cancer, sickle cell anemia, Down syndrome.
2. Stem cell research is one of Sergey Kiselyov's main research interests. These are undifferentiated (immature) cells found in all multicellular organisms. Development begins with them. As a result of numerous cycles of division and the process of differentiation, all types of cells characteristic of this biological species are formed. There are more than 220 such types of cells in the human body. Stem cells are preserved and function in the adult body, thanks to them, the renewal and restoration of tissues and organs can be carried out. However, in the process of aging of the body, their number decreases.
3. Currently, the possibilities of genetic engineering are used to modify the genes of animals and plants, but in the future it is planned to use it for the treatment of hereditary human diseases. So, with the help of gene therapy, it is already possible to give an infertile woman the opportunity to get pregnant, cure color blindness and much more. However, the possibility of making significant changes to the human genome faces a number of serious ethical problems.

On November 30, as part of the Festival of Public Lectures #KNOW, Sergey Kiselyov will devote his story to the topic: "Genes, cells and biotechnologies". The scientist will explain what we know today about the storage and transmission of hereditary information and how we use this knowledge in practice.

The event will take place at the MUSEUM OF MOSCOW at the address: Zubovsky Boulevard, 2. On the territory of the MUSEUM there are buffets, exhibitions are open. Admission is free, the number of seats is limited. Pre-registration on the website "Polit.<url>" and in social media accounts: Facebook, Twitter, LiveJournal, VKontakte.

The lecture starts at 14:00.

Information sponsors are Echo of Moscow radio station, Dilettante magazine, Kommersant FM radio station.

Portal "Eternal youth" http://vechnayamolodost.ru21.11.2014