25 July 2019

Monitor your glucose levels

Scientists told what is dangerous about high blood sugar levels

RIA News

The probability of getting pancreatic cancer increases dramatically even with a slight increase in blood sugar levels, which is typical for both diabetics and quite healthy people. This conclusion was reached by Korean doctors who published an article in the Journal of Clinical Endocrinology & Metabolism (Koo et al., The Incremental Risk of Pancreatic Cancer According to Fasting Glucose Levels: Nationwide Population-Based Cohort Study).

"Everyone knows well that diabetes contributes to the development of pancreatic cancer. Our study shows that early diagnosis of hyperglycemia and a decrease in the proportion of glucose in the body can prolong people's lives and significantly reduce the prevalence of this form of tumors among the population," said Cheol–Young Park from Kambuk-Samsung Hospital in Seoul (in a press release High blood sugar increases pancreatic cancer rate – VM).

According to current WHO data, a global epidemic of obesity has been observed in the world since the 80s of the last century. Every third inhabitant of the globe suffers from extra pounds, and about 15% more from severe forms of obesity. About 47% of diseases, such as atherosclerosis, strokes, heart attacks, diabetes and cancer, are associated with such metabolic disorders.

Sugar and sugary drinks, which have become widely popular around the world in the last two decades, are now claimed to be the main "distributor" of this epidemic, as many doctors and scientists believe today.

The consequences of their spread are already visible today. Two years ago, researchers from the United States found out that excessive consumption of sugary carbonated drinks leads to the death of approximately 184 thousand people every year. Most of these deaths occur in Latin American countries and the United States itself.

Park and his colleagues discovered another negative consequence of sugar abuse by studying data collected by all hospitals in South Korea during routine medical examinations from 2009 to 2013. In total, about 25 million people have passed through doctors, which is actually the entire population of the country.

Analyzing these data, scientists tried to test the popular hypothesis today that sugar not only indirectly contributes to the development of cancer, provoking weight gain and accompanying chronic inflammation, but also directly accelerates the appearance of tumor cells in the human body.

To do this, scientists compared how much sugar was present in the blood of patients with how often they became victims of pancreatic cancer, separately taking into account healthy people and diabetics. Comparing these indicators, scientists tried to understand whether sugar affected their health by itself, or whether its "carcinogenic" properties were manifested only in combination with diabetes.

This analysis unexpectedly showed that the proportion of glucose in the blood affected the likelihood of developing cancer not only at extremely high concentrations, but in fact always. In fact, the chances of acquiring such a tumor gradually grew, starting with the lowest and ending with the highest deviations from the norm in the proportion of sugar.

In particular, high, but quite normal amounts of glucose in the blood were associated with an increase in the likelihood of getting cancer by 17%, a prediabetic condition increased these chances by 50%, and diabetes actually doubled them.

Importantly, the presence of diabetes did not affect this dependence in any way, and its absence or taking insulin did not reduce the likelihood of developing cancer if the concentration of carbohydrates in the body remained high. This suggests that sugar itself contributed to the formation and growth of tumors, and did not accelerate their appearance in indirect ways.

Given the growing number of diabetics and the level of sugar consumption in the world, this discovery and appropriate diagnostic procedures, according to Park and his team, can significantly reduce the prevalence of pancreatic cancer.

To do this, it is necessary that the authorities and medical services of all countries of the world begin to actively monitor the glucose level in the body of all patients, not just diabetics, scientists conclude.

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