New data on the uselessness and even harm of hyaluronic acid in arthrosis
Injections of hyaluronic acid do not help with arthritis of the knee joint
UNIVADISScientists from the University of Bern, Switzerland, warn about this in the journal Annals of Internal Medicine.
After analyzing the data of 89 studies involving 12667 patients conducted from 1966 to 2012, Peter Juni was convinced that the use of hyaluronic acid in knee arthritis is not clinically justified and even dangerous.
Usually, the introduction of drugs into the joint that improve the sliding of articular surfaces facilitates the condition of most patients and reduces joint pain. However, the results of 71 studies involving 9617 patients showed that injections of hyaluronic acid reduce pain by only 0.37 points, which is estimated as a minimal clinical effect. In 18 studies (5,094 patients), the effectiveness was estimated at 0.11 points, i.e. clinically insignificant effect. And in 5 studies (1149 patients), the effect was completely zero and did not exceed the placebo effect.
At the same time, the results of 14 studies (3667 patients) showed a fairly high risk of serious side effects with intra-articular administration of hyaluronic acid. Among them are exacerbation and recurrence of arthritis, the need for prolonged hospitalization and even partial disability, temporary or permanent. "We have not found reliable evidence of the effectiveness of hyaluronic acid in arthritis of the knee joints," Dr. Yuni writes in conclusion. "But we have identified a significant risk of side effects when using hyaluronic acid, although the exact mechanisms of their development are still unknown to us."
Portal "Eternal youth" http://vechnayamolodost.ru22.06.2012