Articles

Biomedicine

Activation of protomitochondria is the path to cell rejuvenation

A curious research project is under consideration at the Eternal Youth Foundation. The data obtained by the author as a result of previous studies supported by the RFBR grant allow us to count on the development of ways to treat mitochondrial encephalomyopathies and slow down and even prevent the aging processes of cells induced by damage to their active oxygen forms by activating the growth of protomitochondria, as well as the elimination of old mitochondrial organelles – postmitochondria.

Biotechnology for Medicine (continued-3)

Natural habitat conditions sometimes demonstrate almost unique capabilities of animals to neutralize toxins or infections.

Stock market 2008 – "hot" five

Fortune magazine included GlaxoSmithKline, one of the world's largest pharmaceutical companies intensively engaged in the development and production of biotechnological drugs, and one Russian company in the top five in terms of investment attractiveness for next year: (true, it has nothing to do with biotech and biopharma):

Biotechnology for Medicine (continued-2)

Despite great success in the creation of synthetic medicines, today interest in the plant and animal world as a source of biologically active substances is constantly increasing.

How to make money on IPO expectations

The statistics of the Russian IPO market show that the shares of most companies fall in price after the initial public offering. Meanwhile, in the process of preparing for the IPO, issuers are restructuring, becoming transparent, and their value is growing rapidly. To participate in the growth that precedes the placement of shares, so-called pre-IPO funds are used.

Pharmaceutical industry: waiting for a deadlock

Competition from generic drugs (copies of original drugs) will lead to a reduction in sales of the largest American companies by $67 billion already in 2007-2012, as patent protection for more than 30 drugs will expire. This is almost half of the total revenue of US companies in 2007. Looking at all this, financial analysts do not recommend investing in the securities of pharmaceutical companies. Experts predict the leadership of biotechnologies, in which generics are technologically and legally impossible.

Ten tips for investors: which stocks to buy

Based on the new realities, it is necessary to follow a fundamentally different investment tactic, different from everything that has been practiced in recent years, says Jonathan Burton. On behalf of MarketWatch, they compiled 10 tips for investors where to direct their money in the next 12 months, so that later it would not be excruciatingly painful for senseless investments.

From flask to sausage

A small addition of substances present in any living cell – nicotinamide dinucleotide (NADH) and adenosine triphosphoric acid (ATP), as well as some harmless dicarboxylic acids – allow you to store ground sausage without spoilage for several weeks, and sausage instead of ten – forty, and not add poisonous nitrates and nitrites to them. But do industrialists accept safer technologies?

Biotechnology for Medicine (continued-1)

The use of natural diversity for therapeutic purposes is not limited only to fungi and actinomycetes that produce antibiotics.

Open, even more open…

Which way should a manager choose – to demonstrate closeness to subordinates or to introduce strict subordination? To what extent and in what way should the doors be "opened" in order to avoid the disadvantages and take advantage of the advantages of such a management style?

Vaccination against monopoly: the mechanism of registration of new vaccines is simplified

From the point of view of business, demonopolization and the involvement of additional state-authorized experts will only benefit, since it will allow more new immunobiological drugs to be brought to the end user faster. The new order is more convenient for everyone, except those who have lost their monopoly.

Biotechnology for medicine

The use of biotechnology of the potential of living organisms in the vital interests of man, his research and economic activities allows solving various problems.

Global pharmaceutical market: state and trends

Despite a slight slowdown in growth this year, the global pharmaceutical market is in excellent condition and on the verge of major changes.

Cloning

Stem cells

"Stem" model of carcinogenesis

The common features of stem and cancer cells allowed us to call malignant ancestral cells cancer stem cells. These cells appear to be the result of a malfunction in the regulatory system of damaged stem cells or their direct descendants.

Is there a connection between the nature of stem cell division and the neoplastic process?

A potential cost for the frequent use of symmetrical stem cell division is an increase in the frequency of cancer that occurs during the transformation of somatic stem cells.

Genetic regulation of stem cell pluripotency (continued)

Embryonic stem cells (ESCs) have a so-called minimal phenotype and a minimum of receptors and programs for interacting with the microenvironment.

Genetic regulation of stem cell pluripotency

Stem cells would not be interesting for developmental biology and clinical medicine if they did not have pluripotency and would not be able to start development again.