Is resveratrol useless for healthy people?
Resveratrol has no therapeutic effect
Elvira Koshkina, This conclusion was reached by scientists from the Medical School of Washington University in St. Louis (USA).
The study involved 29 post-menopausal women who did not have type 2 diabetes and were relatively healthy. During the twelve weeks of the experiment, 15 subjects took an over-the-counter dietary supplement with resveratrol (75 mg of resveratrol per day), and the remaining 14 people received a placebo (sugar tablets). To have 75 mg of resveratrol in everyday life, you would have to drink 8 liters of red wine every day.
At the beginning and end of the study, the participants' insulin sensitivity was measured and glucose intake by their muscles was determined; for this, they were injected with insulin and their metabolic response to various doses was evaluated. As a result, it was not possible to detect the slightest effect from taking resveratrol. The scientists also took small samples of muscle and adipose tissues of the subjects to test the possible effect of resveratrol on cells, but even in this case, the signaling pathways involved in metabolism showed no changes.
The results of the experiment were unexpected, since a number of previous studies have demonstrated that drinking red wine reduces the risk of health problems. However, only a few studies evaluated the effect of resveratrol on people, and even those were conducted with the participation of diabetics, elderly people with impaired glucose tolerance or obese patients who had more metabolic problems than the participants in the experiment under consideration. Thus, it can be assumed that resveratrol can have a beneficial effect on people who are metabolically not quite normal.
But if resveratrol does not bring health benefits, why are red wine lovers less likely to have cardiovascular problems and diabetes? The authors of the work believe that the grape drink may contain some other substances that protect against diseases.
The results of the study are published in the journal Cell Metabolism (Resveratrol Supplementation Does Not Improve Metabolic Function in Nonobese Women with Normal Glucose Tolerance).
Prepared based on the materials of the Washington University School of Medicine in St. Louis:
Resveratrol falls short in health benefits.
Portal "Eternal youth" http://vechnayamolodost.ru26.10.2012