The effectiveness of "calotherapy" has been proven by clinical studies
Stool transplantation was four times more effective than an antibiotic
Copper news based on Nature materials: Faecal transplants succeed in clinical trial
The first clinical trials of an experimental method of treating intestinal infection by fecal transplantation showed such a clear advantage of this method over standard antibiotic therapy that the trials even had to be stopped ahead of schedule. Stool transplantation turned out to be three to four times more effective than an antibiotic. The results of the work are published in the New England Journal of Medicine (Els van Nood et al., Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile).
The essence of the method, called Intestinal Microbiota Transplantation (IMT), is the introduction of a solution of feces taken from a healthy donor into the gastrointestinal tract of patients, resulting in the restoration of normal intestinal microflora. This method of treating diarrhea has been known all over the world for more than half a century, there are about 500 scientific publications proving its effectiveness, but IMT clinical trials were conducted for the first time using the random sampling method.
43 patients suffering from a severe form of resistant recurrent diarrhea caused by Clostridium difficile bacteria became participants in the trials conducted under the guidance of Josbert Keller, a gastroenterologist from the University of Amsterdam. The volunteers were divided randomly – some of them performed IMT procedures using a nasoduodenal probe, and some were prescribed a course of vancomycin.
Initially, the team conducting the trials planned to recruit 120 patients to participate in them, but eventually decided to stop the trials due to the obvious difference in the health status of both groups of volunteers: of the 16 members of the group receiving IMT, 13 fully recovered after the first procedure, two more after the second (94 percent), while of the 26 patients treated with vancomycin, only seven (27 percent) recovered.
Graph from an article in NEJM – VM
The remaining members of this group themselves asked the doctors to perform an IMT procedure for them and recovered after one or two infusions.
The authors hope that the effectiveness of the IMT method demonstrated as a result of the tests will help its widespread introduction into medical practice.
Portal "Eternal youth" http://vechnayamolodost.ru17.01.2013