Prolonging youth
Diet and brain: every vegetable has its time
A low–calorie diet helps to preserve memory in old age, but harms the brain in youth - these are the conclusions of a study conducted by biologists.
19.05.2010- English version
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Life Sciences
Found results: 11545
Biomedicine
Infertility diagnosis: draw the chemical profile of the sperm
The analysis of the chemical profile of individual spermatozoa makes it possible to diagnose infertility more accurately than the assessment of the morphological characteristics of spermatozoa.
19.05.2010
Cellular technologies
The artists are dying one by one. Are stem cells to blame???
V.I. Seledtsov, Professor, MD: "Once again I read that stem cells killed another cultural figure. The situation is getting close to hysteria."
19.05.2010
Biomedicine
"Rejuvenating" steroids for the prevention of cardiovascular diseases
The results obtained do not confirm the rejuvenating effect of steroid hormones. However, steroids can become an effective and inexpensive means of preventing cardiovascular diseases.
18.05.2010
Genetics
Beer belly or curvy hips: the reason is in gene expression
The same expression in fat cells in females and males is characteristic of only 138 out of 40,000 mouse genes.
18.05.2010
Theories of aging
Aging: telomeres + mitochondria + stem cells + …
Degradation of telomeres and activation of p53 expression contribute to disruption of stem cells and mitochondria functions and aging at all levels, from biomolecules to the whole organism. Deciphering the interrelationships of these and other mechanisms of aging will allow us to develop methods for its prevention and rejuvenation of organs and tissues of the elderly.
18.05.2010
New in Gerontology
Are protein plaques the last line of defense against neurodegenerative diseases?
It is believed that protein inclusions in Alzheimer's disease and other neurodegenerative diseases lead neurons to death. However, recent work has shown that perhaps protein plaques are an attempt by neurons to avoid death.
17.05.2010
Cellular technologies
Making artificial organs: the "Lego" principle
The material for the future artificial organ is living cells encapsulated in polymer cubes, from which, as in a children's designer, three-dimensional structures are assembled.
17.05.2010
Other life sciences
Achievements of DNA robotics
The most advanced bionanorobots can walk as many as 50 steps (200 nm) on a DNA-made platform in 40 minutes and even collect nanoparticles of three varieties along the way. While it's still toys…
17.05.2010
Cellular technologies
Eternally young cells and zinc fingers: details
Telomere elongation and genomic stability of embryonic stem cells are regulated by the Zscan4 protein, whose structure includes the zinc finger and SCAN domains.
17.05.2010
Cellular technologies
Endometrial stem cells for the treatment of Parkinson's disease and more
The epithelial cells of the inner surface of the uterus, when implanted into the brain, differentiate into dopamine-producing neurons. The endometrium is the most accessible source of stem cells suitable for the treatment of not only Parkinsonism, but also many other diseases.
14.05.2010
New in Gerontology
Nervous mechanisms of aging and cognitive decline
One of the main health problems faced by the aging generation is the extinction of cognitive function. The mechanisms underlying these processes need to be considered in the context of the molecular biology of the aging process.
14.05.2010
Other life sciences
Unequal marriage and life expectancy
Men whose wives are younger live longer. But the life expectancy of a wife is less, the greater the age difference between the spouses. At the same time, it does not matter whether the wife is older than her spouse or younger.
13.05.2010
Genetics
Is the cause of senile dementia epigenetic changes?
The researchers believe that they have managed to identify an important epigenetic mechanism, the disruption of which can be used as a biomarker of senile dementia.
12.05.2010
New in Gerontology
Another way to prolong life: arrest arrestin
Removal of the arrestin gene from the genome of nematodes led to an increase in the lifespan of these organisms by 30%, while a three-fold increase in the expression of this gene reduced it by 30%.
12.05.2010
Nanotechnology
Delivery of siRNA to tumors: the first nanovector has gone... the second one went...
A multi-stage nanovector siRNA delivery system significantly extends the therapeutic effect of treatment, which has been demonstrated in two independent models of metastatic ovarian cancer in mice.
12.05.2010
Genetic engineering
Gene therapy for prolonging life and treating diseases: from worm to human
The "longevity pills" already found for worms have not yet been developed for humans. Nevertheless, today there is an active search for methods of gene therapy methods for prolonging human life and for the treatment of serious diseases.
12.05.2010
Genetics
Epigenetics: the search for methylated nucleotides is put on the conveyor
Until now, researchers have not had a "streaming" method of working with the epigenome – methylated nucleotides were actually found manually. The authors of the new work proposed a fundamentally different way of searching for epigenetic modifications.
12.05.2010
Biomedicine
Genetically engineered T-lymphocytes: drug synthesis at the patient's home
The RNA switch embedded in T-lymphocytes allows using a chemical signal to stimulate their division and activate the expression of the desired gene, triggering the synthesis of therapeutic molecules directly in the patient's body.
11.05.2010
Genetics
We are all a bit Neanderthal
The results of the rough decoding of the Neanderthal nuclear genome and its comparison with the genomes of modern Europeans, Asians, Papuans and Africans confirmed the version about the crossing of Neanderthals with ancient Europeans.
11.05.2010