Articles

Transcriptome-induced phenotype remodeling

Such a difficult name was given to the method of direct reprogramming of cells without the creation of induced pluripotent stem cells and their transformation into target cells and without the use of various growth factors.

If only the human liver…

With the help of capsules with human liver tissue implanted in laboratory mice, it will be possible to study the effects of new drugs on the liver, which was previously impossible due to the different reactions of mice and humans to chemical compounds.

Nanotowars with four letters

According to the decree of the Government of the Russian Federation, nanoindustry goods and services are divided into four categories: "A", "B", "C" and "D".

Cannabinoid receptors protect the brain from aging

The absence of type 1 cannabinoid receptors (CB1) is associated with the rapid development of symptoms of brain degeneration similar to those observed in patients with senile dementia.

Glamorous innovations

The first boutique where you can buy an innovative idea has opened in Russia. The projects were presented to potential business angels by well-known figures of show business.

IPSK: problems of transition age

Induced pluripotent stem cells are one of the newest areas of biology that is rapidly gaining momentum. Like any other new science, it has now entered a difficult "teenage" period.

I just remember that the walls are with wallpaper…

Steroid hormones, the synthesis of which by hippocampal neurons is triggered by large doses of ethanol, are to blame for memory lapses the morning after drinking.

Hands off beta cells!

The introduction of the CCL22 protein gene into the beta cells of the pancreas of mice with a model of diabetes stops the autoimmune reaction and protects the subjects from type 1 diabetes.

Artificial trachea on a plastic frame

First, a Y-shaped base was created from a new plastic-like nanocomposite polymer. Two days later, the patient's stem cells were placed there, where they were grown to tracheal cells ready for transplantation.

Stem cells labeled "extra pure"

For the first time in the half-century history of stem cell research, biologists have isolated the purest population of hematopoietic cells. To catch each such cell, they had to "filter out" about two hundred thousand umbilical cord blood cells.

References to the article "The Mystery of longevity"

The mystery of longevity

Why human life expectancy has been increasing rapidly in recent decades: solving the "mystery of longevity" with the help of the hypothesis of "manifested slow aging".

Give birth to healthy children!

According to the new law, couples can use preimplantation genetic diagnostics if, due to hereditary diseases of the parents, there is a high probability of the birth of a seriously ill or dead child, as well as a miscarriage.

Gold nanoparticles will block the blood supply to the tumor

Scientists from the University of Southampton have developed "smart" nanomaterials that disrupt the blood supply to cancerous tumors.

Obesity is a slow suicide

In heart failure, which occurs due to obesity, special regulatory molecules of small nucleolar RNAs are "guilty", which, with an increase in the concentration of fatty acids in the cell, trigger the procedure of cellular suicide.

Treatment of parkinsonism: dopamine neurons from fibroblasts

Scientists have taken a decisive step in the fight against Parkinson's disease. Dopamine neurons – cells whose death causes the symptoms of Parkinsonism – can be grown from the skin of the person himself.

Foggy Innograd

The Russian Silicon Valley, the Skolkovo Innovation Center, has started its work. However, it remains unclear what Skolkovo is, how this center will work and what to expect from it.

We stop growing and multiplying – we move on to prolonging life!

Suppression of the mRNA translation factor of the IFG-1 gene causes the redistribution of the resources of the adult worms from the growth and reproduction regime to the preferential preservation of somatic cells, which prolongs their life by 40%.

43rd European Human Genetics Conference through the eyes of a participant

The 43rd Annual Conference on Human Genetics (ESHG 2011) was held in Amsterdam from May 28 to May 31, 2011.

Embryoid bodies on the conveyor

It takes about 10 minutes to manually prepare one drop, in which the embryoid body will then develop. The bioprinter prints rows of microscopic droplets with a suspension of embryonic stem cells at a rate of up to 160 drops per second.