18 December 2017

Spermobots continue to work

Sperm has found an unexpected use in women's health

Tape.roo

German scientists (not for the first time – VM) suggested using sperm cells to treat cancer. The study is published in ACS Nano (Xu et al., Sperm-Hybrid Micromotor for Targeted Drug Delivery, reports New Scientist (Hijacked sperm carry chemo drugs to cervical cancer cells).

Sperm-Hybrid.gif
Figure from the article in ACS Nano – VM.

In their experiments, specialists used spermatozoa for the point delivery of the antitumor drug doxorubicin to the cancerous tissues of the uterus. For this purpose, pretreated spermatozoa (doxorubicin actively penetrates into the heads of male germ cells) were supplied with magnetic micromotors controlling the direction of movement.  After reaching the tumor tissue, the sperm attached to the wall of the cancer cell, and doxorubicin began to penetrate from its head into the latter. In this way, 87 percent of cancer cells were destroyed in three days.

   

According to the World Health Organization, about 300 thousand women die from cervical cancer every year in the world. To prevent the disease, the international organization recommends vaccinating girls aged 9-13 years with a vaccine against human papillomaviruses, which are associated with most cases of cervical cancer.

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