16 November 2015

The patch will detect inflammation

The new patch changes color when the wound is infected



Toby Jenkins explains that the patch is made of hydrated agarose containing nanocapsules with a fluorescent dye. The dye is released under the action of toxins synthesized by pathogenic bacteria.


A snapshot from the article by Thet et al. Prototype Development of the Intelligent Hydrogel Wound Dressing
and Its Efficacy in the Detection of Model Pathogenic Wound Biofilms
 
(ACS Applied Materials & Interfaces, 2015) – VMScientists have already found out that the patch reacts to the presence of microorganisms such as E. coli, Pseudomonas aeruginosa, Staphylococcus aureus and fecal Enterococcus.

It is known that bacteria form biofilms on the surface of wounds. The authors showed that the higher the probability of biofilm formation by microorganisms causing infections, the more the patch color changes. The patch is able not only to detect the infection, but also to determine which bacteria caused it. The authors hope that they will soon be able to test the novelty on patients.

(Two and a half years ago, the same researchers announced that they planned to start clinical trials and test the safety of the same "smart bandage" on healthy volunteers, and later on on patients with burns. We are waiting for... - VM.)

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16.11.2015
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