Choose the right antiseptic

The microbiologist of ChelSU explained why popular antiseptics do not help in the treatment of burns

ChelSU Press Service

Why can't the treatment of burns by traditional methods always be effective? It turns out that various pathogens of infections are concentrated in the wounds, which form a biological film on its surface that prevents the penetration of disinfecting drugs.

The research of Svetlana Andreeva, an assistant of the Department of Microbiology, Immunology and General Biology of Chelyabinsk State University, Candidate of Biological Sciences, helps to solve this problem. She suggested a strategy for choosing antiseptics for the treatment of burns so that the patient recovers as quickly as possible. It is based on the determination of the types of microorganisms in the wound, the characteristics of their interaction and sensitivity to drugs. Scientists simulate "in vitro" those bacterial biofilms, study bacteria and their resistance to antiseptics and other antibacterial drugs.

Svetlana Andreeva worked with data obtained from 3926 patients, determined the change of microbial communities of wounds during burn disease and found that Staphylococcus aureus and Pseudomonas aeruginosa are often found in the microflora of wounds. In addition, having studied the activity of antiseptics on planktonic and biofilm forms of bacteria, the microbiologist for the first time established that the long-term use of furacilin, boric acid, miramistin and chlorhexidine in the treatment of wound infections leads to a loss of their effectiveness.

Today, this method of determining the effectiveness of antiseptic drugs against biofilm forms of bacteria is patented.

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