Dementia risk assessed by faeces
The connection between intestinal bacteria and disorders in the brain was found
The results of the study conducted by the staff of the National Center of Geriatrics and Gerontology (Japan) were presented during the International Stroke Conference 2019 held in Honolulu.
Scientists studied fecal samples of 128 people, some of whom were diagnosed with dementia. Tests have shown that in the feces of patients with dementia, some substances formed in the intestine as a result of the activity of bacteria living there are contained in higher concentrations than in healthy people. We are talking about such compounds as ammonia, phenol, indole and skatol. In addition, the feces of patients with dementia contained fewer bacteroids (Bacteroides) – microorganisms most extensively represented in the normal intestinal microflora.
The researchers suggest that the abnormalities they found indicate characteristic disorders in the community of bacteria and microbes living in the digestive tract of patients with dementia. Thus, what is happening in the intestinal microflora may be the same risk factor for dementia as other factors.
"Although this is only an observational study so far, and we have examined a very small number of patients, there is a lot of chance that intestinal bacteria can become an object of exposure in order to prevent dementia," said Naoki Saji, lead author of the study.
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