15 September 2016

I begot you…

Skin cancer can be defeated by sunlight – scientists

IA REGNUM

American specialists managed to dramatically slow down the growth of cancer cells by exposing them to sunlight. Before that, the DNA of cancer cells was altered in a special way, the Journal of the American Chemical Society reports.

Shedding-light.jpg

Figure from the article by Pollum et al. Unintended Consequences of Expanding the Genetic Alphabet. A short retelling of the work can be read in the press release Shedding light on the limits of the expanded genetic code - VM.

Previously, it was found that the DNA of cells is sensitive to ultraviolet radiation. At the same time, living cells are able to restore the genetic code after damage caused by UV rays.

Scientists from Case Western Reserve University in Cleveland have created nucleosides, components of nucleotides in DNA and RNA that are able to absorb light more strongly in the visible part of the spectrum. Then artificial nucleosides d5SICS and DNAm were introduced into skin cancer cells.

It turned out that under the influence of ordinary sunlight, the growth of cancer cells slowed down. The content of reactive oxygen species in them, responsible for the destruction of the cell, has increased markedly. According to scientists, their developments can be used in the future to fight human skin cancer.

Portal "Eternal youth" http://vechnayamolodost.ru  15.09.2016


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