Prospects for dentists: "the gene of tooth enamel"

Researchers from the University of Oregon have described a gene that controls the formation of tooth enamel – the outer protective shell of teeth. The discovery may lead to the emergence of fundamentally new methods of prevention and treatment of caries, as well as become the basis for growing teeth in the laboratory, the journal The Proceedings of the National Academy of Sciences reports.

The gene described by scientists called Ctip2 is responsible for the synthesis of transcription factors (proteins that control the transfer of information from the DNA molecule into the mRNA structure) and performs a number of functions. In particular, it participates in the regulation of the immune response, the development of the skin and nervous system. In experiments on mice, it was also found that this gene controls the formation and maturation of ameloblasts – cells that produce tooth enamel, said the head of the study.  Chrissa Kioussi.

Previously, in experiments, scientists managed to grow only the internal elements of teeth. New data opens the way to the artificial creation of "full-fledged" teeth covered with enamel. In addition, gene therapy opens up new opportunities for strengthening and restoring damaged tooth enamel, as well as the prevention and treatment of caries, scientists believe.

Copper News based on the materials of Science Daily: Genetic Discovery Could Lead To Advances In Dental Treatment

Portal "Eternal youth" www.vechnayamolodost.ru25.02.2009