16 June 2009

Two more multiple sclerosis genes

New genes involved in the development of sclerosis have been identifiedElena Novoselova (Live Systems)
 based on the materials of The University of MelbourneA group of scientists from Australia and New Zealand has discovered the location of two new genes responsible for the development of multiple sclerosis.

This discovery will help to uncover the causes of multiple sclerosis and other autoimmune diseases.

Scientists from the University of Melbourne (University of Melbourne) and the Howard Florey Neurosciences Institutes (Howard Florey Neurosciences Institutes) have discovered two loci of genes that cause the development of multiple sclerosis, located on the twelfth and twentieth chromosomes. This discovery helps to understand the causes and mechanisms of genetic susceptibility to multiple sclerosis and other autoimmune diseases, including type 1 diabetes, rheumatoid arthritis and Basedova disease.

More than 40 researchers from 11 institutions in Australia and New Zealand participated in the research conducted by members of the ANZgene association. For three years, the genetic materials of 1,618 people with multiple sclerosis and 3,413 healthy people (control group) were studied. After the discovery of the location of the genes responsible for the development of multiple sclerosis, scientists plan to create accurate genetic maps and identify the molecular mechanisms of gene action.

The results of the work are published in the journal Nature Genetics.

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