Urine analysis instead of biopsy
The biopsy will be replaced with a simple analysisНовости@mail.ru
Olga Novoselova, a young employee of the Russian Scientific Center of Surgery of the Russian Academy of Medical Sciences, has come up with a diagnostic method that will save patients with a transplanted kidney from regular unpleasant studies. The method has no analogues in the world.
Kidney transplantation, like any other transplantation, actually gives a person a second life. But his trials don't end there. Every six months, or even more often, he has to undergo a painful biopsy procedure. A piece of tissue is taken from the transplanted kidney through a puncture to see if there is a threat of rejection.
Olga Novoselova, a graduate of the Russian State Medical University, under the guidance of Mikhail Kaabak, head of the Organ Transplantation Department, and Yuri Mikhailov, head of the Laboratory of Clinical Biochemistry, collected material about the rejection reaction, studied hundreds of analyzes of the center's patients, the spectrum of proteins that appear in urine during rejection. And she isolated marker proteins that absolutely accurately predict: an undesirable reaction has begun, it is necessary to take emergency measures that will save both the transplanted organ and the patient's life.
– When I started the work, I did not think that it would give such a practical result, – Olga told Izvestia. – I really hope that over time our work will be appreciated in other clinics, and examinations will be much easier for patients.
And senior colleagues have already appreciated the work of the young candidate of sciences – Olga recently defended her dissertation. Today, at the traditional annual assembly day, she will be awarded an honorary diploma and an award for the best scientific work of the year. Usually such distinctions are received by honored and venerable – professors and academicians.
– Olga's work is undoubtedly world–class and is absolutely rightfully recognized by the Scientific Council of the center, - says the director of the RNC, Professor Sergey Dzemeshkevich, commenting on the award. – We are glad that we have a whole cohort of young and promising researchers and doctors.
Most patients who have had a kidney transplant at the RNCC now do not have to undergo regular biopsies, it is enough to pass a banal urine test. And Olga and her colleagues have more than enough prospects for further research: the center performs transplants of all vital organs – more than a hundred a year.
Portal "Eternal youth" http://vechnayamolodost.ru/26.06.2009