Vaccines based on matrix RNA
Moderna plans to test an HIV vaccine in 2021. The coronavirus vaccine helped in its development
The American biotech company Moderna, which has produced two coronavirus vaccines, will develop three new vaccines in 2021. Among them is a drug for HIV infection, seasonal flu and the Nipah virus, which causes severe inflammation of the brain. The company announced this on its website.
The HIV vaccine, in particular, is being developed in collaboration with the International AIDS Vaccine Initiative and the Bill and Melinda Gates Foundation. The first phase of testing of the drug should begin in 2021. The flu vaccine will be able to prevent the disease not only with ordinary flu, but also with coronavirus. It will also be tested this year.
All new vaccines will be based on the matrix RNA of the virus, thereby differing from traditional drugs. To put it simply, such vaccines seem to give the human body instructions on how to build special proteins that trigger natural immune defense. Such "instructions" are valid for a limited amount of time and do not affect human DNA. The produced proteins block viral particles. After they do their job, the body will automatically destroy them.
The development of RNA-based vaccines has great potential for the production of future antiviral drugs. Such vaccines are more flexible, their action can be "programmed", while they do not contain an active or dormant form of the virus, which reduces the risk of infection of the patient. The accelerated development of RNA vaccines became possible thanks to the coronavirus pandemic – more money began to be invested in this field of science, government agencies also became interested in it, writes the TechCrunch portal.
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