Another useful property of aspirin
Doctors: aspirin blocks the growth of breast cancer and prevents its spread
RIA NewsExperiments on cancer cell cultures and tumors in mice have shown that aspirin and other drugs based on it block the growth of breast cancer and prevent it from spreading to other parts of the woman's body, which will help protect patients from metastases, scientists say in an article in the journal Laboratory Investigation (Maity et al., Aspirin blocks growth of breast tumor cells and tumor-initiating cells and induces reprogramming factors of mesenchymal to epithelial transition – VM.)."The problem is that in many cases the disease returns 5-10 years after treatment. Some of the cancer cells are a kind of stem cells that survive chemotherapy and go into "sleep mode", in which they remain until the conditions inside the body become favorable. When they wake up, they turn into extremely aggressive and almost untreatable tumors," explains Suschanta Banerjee from the University of Kansas in Kansas City (in an article on the website of the US Department of Veterans Affairs Research: Daily aspirin could block growth of breast, other cancers http://www.research.va.gov/currents/spring2015/spring2015-25.cfm – VM).
Banerjee and his colleagues found a potential solution to this problem and simultaneously revealed the strong anti-cancer properties of aspirin by observing the reaction of cancer cell cultures and tumors grown in the mouse body to molecules of various drugs.
As this experiment showed, acetylsalicylic acid molecules had an extremely negative effect on the vital activity of breast cancer cells – with large doses of aspirin, they simply died, and with relatively small concentrations of the drug, their growth stopped.
A similar reaction was observed both in cell cultures and in the body of experimental animals. In particular, the size of tumors in the body of mice who ate aspirin was on average 47 less than in individuals from the control group.
The positive properties of aspirin were not limited to this – as doctors found out, its molecules block the transformation of the connective tissue of the breast and its other components into a special subspecies of cancer cells that have the ability to move independently and go into "sleep mode".
According to scientists today, such cells are one of the causes of breast cancer metastasis and its ability to "resurrect" a few years after the removal of the tumor and the completion of chemotherapy.
For this reason, Banerjee believes that taking aspirin after chemotherapy or just regular use of this medication can protect women from metastasis or even the appearance of breast cancer.
As the doctor warns, when using aspirin, care should be taken – it does not have a very beneficial effect on the work of the stomach and intestines, and also changes the composition of the blood. For this reason, you should not run to the pharmacy, buy aspirin and be treated yourself, without prior consultation with a therapist, the scientist concludes.
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16.06.2015