Analysis for myocardial ischemia

A group of scientists from Duke University presented data from a pilot study devoted to the development of a method for detecting blood supply disorders of the heart muscle. The study involved patients admitted to the emergency department with symptoms of acute coronary syndrome.

The researchers conducted a treadmill stress test for each patient - an electrocardiographic study during exercise (running on a treadmill). Based on the results of this test, 20 people were selected in whom the stress test showed signs of stress-induced myocardial ischemia. Then, among those who had no such signs, a control group of 20 people was recruited.

An hour before the start, immediately after the test and after two hours, blood samples were taken from the subjects. The blood test was performed on 60 indicators, five of which (metabolites of fatty acids and amino acids) changed two hours after the stress test.

Stress test is a common technique that allows you to identify those who are at risk for the development of cardiovascular diseases, and who need more serious and invasive studies. Previous studies have shown that metabolites can indicate heart disease, but until now it was not clear what exactly researchers should pay attention to.

Scientists hope that further studies will help to confirm the significance of changes in the concentration of these biomarkers for the early diagnosis of blood flow disorders.

Article by Limkakeng et al. Pilot study of myocardial ischemia-induced metabolic changes in emergency department patients undergoing stress testing is published in PLOS one.

Anastasia Poznyak, portal "Eternal Youth" http://vechnayamolodost.ru / based on Duke Health: Blood Test for Specific Metabolites Could Reveal Blocked Arteries.