03 November 2016

The main innovations in medicine

Top 10 medical innovations according to the Cleveland Clinic

Weekly Pharmacy apteka.ua based on the materials of the Cleveland Clinic: Cleveland Clinic announces top 10 medical innovations for 2017

Specialists of the Cleveland Clinic (USA) have prepared another annual list of medical innovations that, in their opinion, will have the greatest impact on the healthcare system in the coming 2017. This is the 11th list prepared by specialists.

1. The use of the microbiome for the prevention, diagnosis and treatment of diseases.
Over the past 10 years, researchers have found that chemicals secreted by representatives of the human microflora have an effect on food digestion, pharmacokinetics of drugs and the progression of various diseases. Currently, research is actively underway to develop new tools for the diagnosis and treatment of various diseases based on probiotic products. According to experts at the Cleveland Clinic, this will be one of the promising areas in medicine next year.

2. Medicines for the treatment of diabetes mellitus that reduce the risk of developing cardiovascular diseases and death. The development of new products intended for the treatment of diabetes mellitus gives chances to reduce the risk of complications of this pathology and increase the life expectancy of such patients.
Thus, empagliflozin, in addition to lowering blood glucose levels, affects the progression of cardiovascular diseases by affecting kidney function, and liraglutide additionally has a complex effect on many organs. Experts predict that in 2017, scientists will look for new ways and goals for the treatment of type II diabetes.

3. Cellular immunotherapy of leukemia and lymphomas. New developments for the purpose of immunotherapy of oncopathology give hope for the development of a promising treatment for leukemia and non-Hodgkin's lymphoma, even in the late stages.
The technology of using a chimeric antigen receptor (Chimeric antigen receptor – CAR) allows reprogramming the patient's own immune cells outside his body in order to create a CAR that allows detecting tumor cells and effectively destroying tumors in the patient. The resulting CAR cells are then used for immunotherapy of oncopathology. It is expected that next year scientists will continue their research in this area and present their results in the United States regarding the use of immunotherapy for the treatment of acute lymphoblastic leukemia.

4. "Liquid biopsy" to search for the DNA of circulating tumor cells.
The concept of "liquid biopsy" is planned to be used as a new diagnostic method in order to identify the DNA of tumor cells and establish a diagnosis of oncopathology. Several companies are developing diagnostic kits based on this technology, which may appear on the market next year.

5. Automated car and driver safety functions. New automatic safety features in the car can help reduce the number of road accidents, which remain one of the leading causes of death and disability in many countries.
Automated functions include collision warning systems, driver drowsiness, and adaptive cruise control.

6. The system of interaction of medical resources.
For many years, doctors, insurance companies and other providers have been working with databases that do not have the ability to interact with each other. Experts predict that in 2017 the possibility of communication between different databases of medical data will be implemented. So, it is planned to launch a tool that ensures compatibility between various resources in the field of healthcare – Fast Healthcare Interoperability Resources, FHIR.

7. Ketamine for the treatment of resistant depression.
About 1/3 of patients with depression do not feel any improvement in their condition after taking antidepressants. Initial studies showed that 70% of patients with therapy–resistant depression experienced a decrease in the severity of symptoms within 24 hours after receiving low doses of ketamine, a drug widely used for anesthesia. It is assumed that ketamine-based drugs intended for the treatment of depression will appear on the US market next year.

8. 3D visualization and augmented reality in the field of surgery.
Experimental 3D imaging technology designed for surgeons is designed to provide additional comfort and visual information during surgery in order to improve the efficiency and quality of doctors' work. In turn, augmented reality glasses that display holographic images of human anatomy can benefit medical schools.

9. Self-test for human papillomavirus (HPV). Prevention and treatment of HPV is an important aspect of reducing the risk of cervical cancer.
It is expected that next year HPV detection kits developed by scientists will be available to consumers in order to be able to send the collected samples to the laboratory by a woman.

10. Bio-soluble stents.
There is an opinion that the presence of a stent for a long time leads to thrombosis, therefore, work was initiated to create bio-soluble or absorbable stents made of a natural polymer capable of resorption in the body. This technology was developed by analogy with absorbable filaments, which dissolve in the body some time after surgery. The first absorbable stent was approved in the USA in July of this year. Experts believe that the market for bio-soluble stents will amount to about $ 2 billion. USA in the next 6 years.

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