16 October 2017

Anti-cancer eggs

Genetically Modified Chicken Eggs contain Cancer Cure

Ksenia Malysheva, Naked Science

Publication The Japan News has published a report that researchers from the National Industrial and Technological Institute (AIST) have successfully completed experiments on the genetic modification of cock germ cells. Eggs fertilized by GM sperm develop into eggs in which beta-interferon is actively synthesized - a protein very important for the functioning of the human immune system, an active component of drugs for many types of cancer and hepatitis.

The genes encoding beta-interferon were introduced into the cells that produce rooster sperm. Then hen eggs were fertilized with GM sperm and the first generation of roosters was obtained, in whose testes GM sperm were produced without the intervention of geneticists. A few generations later, a new breed of chicken with fixed genetic modification appeared. The analysis confirmed that the egg protein of chickens of this breed is rich in interferon (specific figures are not reported).

The result of the experiments is three hens laying eggs every one or two days. In the future, researchers plan to increase the content of interferon in protein to 100 mg; this should dramatically reduce the cost of production of the drug, the cost of which today reaches 50 thousand rubles. for a dose of several milligrams. Currently, human interferons are produced using a genetically modified strain of the bacterium E. coli, sometimes (extremely rarely) by chemical synthesis. Sometimes it is not interferon itself that is injected into the patient's body, but its inducers – substances that stimulate the production of interferon by cells of the immune system.

The technology was developed by biotechnologists of the Tokyo company Cosmo Bio Co. with the support of AIST and the National Organization for Research in the Field of Agrotechnologies and the Food Industry.  

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