24 March 2016

GM maggots against wound infections

Larvae of transgenic carrion green flies
they will begin to use it for wound healing

Medical news based on Medicalexpress materials: NC State University: Modified maggots could help human wound healing

Flies and their larvae are associated with unsanitary conditions and infection. New Zealand scientists have proposed genetically modifying carrion green flies (Lucilia sericata) and using their larvae to accelerate wound healing.

Max Scott and his colleagues explained that larval therapy, the process of cleaning wounds with the help of larvae of some flies, will help to cope with wounds that heal poorly. This method has been known for a long time and is widely used to combat foot ulcers in diabetes. However, evidence that such therapy accelerates wound healing has not been previously obtained.

Transgenic larvae are able to produce platelet growth factor (PDGF-BB), which stimulates cell division and growth – under its action, wounds heal faster. The secretion of the growth factor began only when tetracycline was excluded from the nutrient medium on which the larvae were grown.

The authors believe that their proposed technique will help people avoid amputations. In the near future, they plan to create lines of transgenic flies whose larvae will express other growth factors and antimicrobial peptides.

Portal "Eternal youth" http://vechnayamolodost.ru  24.03.2016

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