Vaccines in nanoparticles
Nanoprinting of vaccines is proposed
Joseph Desaimon and his company Liquidia (USA) announced the nanoproduction process for vaccines at the annual conference of the American Chemical Society held in San Diego, expressing hope that the work will help improve the immunological situation in developing countries.
Mr. Desaimon has achieved considerable success in the field of mass production of nanoparticles using nanolithography: materials are cast into molds and then transferred to film in a direct-flow process. Now he and his company have decided to merge their experience and knowledge with the precision and uniformity of the microelectronic industry for the production of vaccines and medicines.
Nanoprinting of viral proteins and bacterial sugars
will help make vaccines cheaper and more effective
(illustration by Joseph DeSimone).
It is well known that the properties of nanoparticles – shape, charge, a certain flexibility – can be reflected in which corner of the body these particles will be after their introduction. This feature has a huge potential for both targeted delivery of funds to the destination inside the body and for vaccination. Manufacturers are trying less and less to use vaccines based on live viruses or bacteria, replacing them with products that contain specific proteins that make up the shells of viruses, or polysaccharides characteristic of bacterial shells. But, unfortunately, such "safe" drugs are not so effective, because our immune system still reacts to individual small molecules differently than to full-fledged objects (bacteria and viruses in the shell).
Combining these viral proteins or bacterial sugars with nanoparticles can significantly improve the effectiveness of "safe vaccines". One of these vaccines from Liquidia is currently undergoing the first phase of clinical trials, and several more are in development.
Prepared according to the materials of the Royal Chemical Society: Printing vaccines for the masses with nano-fabricationPortal "Eternal youth" http://vechnayamolodost.ru