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Bone marrow transplantation without chemo and radiotherapy
The new approach increases the safety of hematopoietic stem cell transplantation, significantly expanding the possibilities of using this technology.
23 August 2016 -
The dangerous complication of bone marrow transplantation was suppressed
Blocking the interferon-gamma receptor prevents the development of a graft-versus-host reaction after bone marrow transplantation, while simultaneously stimulating the graft-versus-leukemia effect.
11 October 2012 -
Snips will help prevent a graft-versus-host reaction
The results of the study showed that the mismatch of only two single nucleotide polymorphisms (snips) in the donor and recipient is associated with an increased risk of acute GVHD and death of the patient.
17 September 2012 -
Pig beta cells have been taught to deceive the immune system
Transplantation of beta cells of genetically modified pigs normalizes glucose metabolism in the body of humanized mice, without causing the development of a rejection reaction.
27 April 2012 -
Transplantation from immunocompatible donors: the first success
Five out of eight patients within a year after kidney transplantation, who did not fit them according to immunological parameters, together with hematopoietic stem cells from donors, were able to refuse to take immunosuppressants.
13 March 2012